Mariana Kaplan, M.D.

Senior Investigator
Chief of the Systemic Autoimmunity Branch
Deputy Scientific Director at the NIH

Dr. Kaplan is Chief of the Systemic Autoimmunity Branch and Deputy Scientific Director at the National Institute of Arthritis and Musculoskeletal and Skin Diseases at the NIH.


Before her appointment, she was a Professor of Medicine in the Division of Rheumatology at the University of Michigan. She is an Internist and a Rheumatologist. Her research focuses on characterizing the role of the innate immune system in the development of systemic rheumatic diseases such as systemic lupus erythematosus and rheumatoid arthritis. Her lab has focused on the role of neutrophils and neutrophil extracellular traps in autoimmunity, chronic inflammatory diseases and vasculopathy. Dr. Kaplan also investigates mechanisms of vascular damage in autoimmunity.


Dr. Kaplan has served in numerous roles at the American College of Rheumatology/Rheumatology Research Foundation, the American Association of Immunologists, and the Lupus Foundation of America. She was inducted to the American Society for Clinical Investigation and the Association of American Physicians and received the Henry Kunkel Young Investigator Award from the American College of Rheumatology and the Evelyn Hess Award from the Lupus Foundation of America. Dr. Kaplan is on the Editorial Board of the Journal of Clinical Investigation and is Deputy Editor of Arthritis & Rheumatology.